B cell-rich niches support stem-like CD8+ T cells in cancer microenvironment

Cancer Cell. 2023 May 8;41(5):824-825. doi: 10.1016/j.ccell.2023.04.007.

Abstract

Cytotoxic T cells are indispensable for the body's fight against most cancers. In the current issue of Cancer Cell, Gaglia et al. reveal how changes in the tumor tissue architecture creating niches of T cell-B cell interactions may support anti-tumor T cell responses.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Antibodies
  • B-Lymphocytes
  • CD8-Positive T-Lymphocytes*
  • Humans
  • Neoplasms* / therapy
  • T-Lymphocytes, Cytotoxic
  • Tumor Microenvironment

Substances

  • Antibodies