Aberrant activation of TRIP13-EZH2 signaling axis promotes stemness and therapy resistance in multiple myeloma

Affiliations

• ¹ Department of Hematology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
• ² Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, 200072, China.
• ³ CAS Key Laboratory of Receptor Research; State Key Laboratory of Drug Research; Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
• ⁴ Myeloma Center, Winthrop P. Rockefeller Cancer Institute, Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
• ⁵ Department of Hematology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200120, China. shijumei@tongji.edu.cn.