Extending Chirality in Group XIV Metallatranes

Britta Glowacki-Pallach; Michael Lutter; Dieter Schollmeyer; Wolf Hiller; Viatcheslav Jouikov; Klaus Jurkschat

doi:10.1021/acs.inorgchem.2c04242

Extending Chirality in Group XIV Metallatranes

Inorg Chem. 2023 May 22;62(20):7662-7680. doi: 10.1021/acs.inorgchem.2c04242. Epub 2023 May 8.

Authors

Britta Glowacki-Pallach¹, Michael Lutter¹, Dieter Schollmeyer², Wolf Hiller¹, Viatcheslav Jouikov³, Klaus Jurkschat¹

Affiliations

¹ Fakultät für Chemie und Chemische Biologie, Technische Universität Dortmund, 44221 Dortmund, Germany.
² Institut für Organische Chemie, Johannes Gutenberg-Universität Mainz, 55099 Mainz, Germany.
³ UMR 6226 - ISCR, University of Rennes, 35042 Rennes, France.

PMID: 37156016
DOI: 10.1021/acs.inorgchem.2c04242

Abstract

The syntheses of the racemic amino alcohol rac-N(CH₂CMe₂OH)(CMe₂CH₂OH)(CH₂CHMeOH) (L^{22'1^*}H₃, 2) and its representative N(CH₂CMe₂OH)(CMe₂CH₂OH)(CH₂C(R)HMeOH) (L^22'1RH₃, 3) with the stereogenic carbon center being R-configured are reported. Also reported are the stannatranes L^{22'1^*}SnOt-Bu (4) L^22'1RSnOt-Bu (6) and germatranes L^{22'1^*}GeOEt (5) and L^22'1RGeOEt (7) as well as the trinuclear tin oxocluster [(μ₃-O)(μ₃-O-t-Bu){SnL^22'1R}₃] (8). NMR and IR spectroscopy, electrospray ionization mass spectrometry (ESI MS), and single crystal X-ray diffraction analysis characterize these compounds. Computational studies accompany the experimental work and help understand the diastereoselectivity observed in the course of the metallatrane syntheses.