Imaging Assessment of the Efficacy of Chemotherapy in Primary Malignant Bone Tumors: Recent Advances in Qualitative and Quantitative Magnetic Resonance Imaging and Radiomics

Xiaoge Liu; Zhiqing Duan; Shaobo Fang; Shaowu Wang

doi:10.1002/jmri.28760

Imaging Assessment of the Efficacy of Chemotherapy in Primary Malignant Bone Tumors: Recent Advances in Qualitative and Quantitative Magnetic Resonance Imaging and Radiomics

J Magn Reson Imaging. 2024 Jan;59(1):7-31. doi: 10.1002/jmri.28760. Epub 2023 May 8.

Authors

Xiaoge Liu¹, Zhiqing Duan¹, Shaobo Fang^{2

3}, Shaowu Wang¹

Affiliations

¹ Department of Radiology, The Second Hospital, Dalian Medical University, Dalian, China.
² Department of Medical Imaging, Zhengzhou University People's Hospital and Henan Provincial People's Hospital, Zhengzhou, Henan, China.
³ Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China.

PMID: 37154415
DOI: 10.1002/jmri.28760

Abstract

Recent studies have shown that MRI demonstrates promising results for evaluating the chemotherapy efficacy in bone sarcomas. This article reviews current methods for evaluating the efficacy of malignant bone tumors and the application of MRI in this area, and emphasizes the advantages and limitations of each modality. LEVEL OF EVIDENCE: 5 TECHNICAL EFFICACY: Stage 2.

Keywords: Ewing's sarcoma; magnetic resonance imaging; osteosarcoma; quantitative imaging; radiomics; response to treatment.

Publication types

Review

MeSH terms

Bone Neoplasms* / diagnostic imaging
Bone Neoplasms* / drug therapy
Bone Neoplasms* / pathology
Humans
Magnetic Resonance Imaging
Osteosarcoma* / diagnostic imaging
Osteosarcoma* / drug therapy
Sarcoma, Ewing* / drug therapy
Sarcoma, Ewing* / pathology

Grants and funding

No. 82271975/National Natural Science Foundation of China