Microneedle arrays integrated with microfluidic systems: Emerging applications and fluid flow modeling

Abdollah Ahmadpour; Pelin Kubra Isgor; Berk Ural; Busra Nimet Eren; Misagh Rezapour Sarabi; Metin Muradoglu; Savas Tasoglu

doi:10.1063/5.0121578

Microneedle arrays integrated with microfluidic systems: Emerging applications and fluid flow modeling

Biomicrofluidics. 2023 Apr 10;17(2):021501. doi: 10.1063/5.0121578. eCollection 2023 Mar.

Authors

Abdollah Ahmadpour¹, Pelin Kubra Isgor², Berk Ural¹, Busra Nimet Eren¹, Misagh Rezapour Sarabi¹, Metin Muradoglu¹, Savas Tasoglu

Affiliations

¹ Department of Mechanical Engineering, College of Engineering, Koç University, Türkiye.
² Department of Biomedical Sciences and Engineering, College of Engineering, Koç University, Türkiye.

Abstract

Microneedle arrays are patches of needles at micro- and nano-scale, which are competent and versatile technologies that have been merged with microfluidic systems to construct more capable devices for biomedical applications, such as drug delivery, wound healing, biosensing, and sampling body fluids. In this paper, several designs and applications are reviewed. In addition, modeling approaches used in microneedle designs for fluid flow and mass transfer are discussed, and the challenges are highlighted.

Publication types

Review