Parameters to consider for successful medication use in older adults - An AGePOP review

Eur J Pharm Sci. 2023 Aug 1:187:106453. doi: 10.1016/j.ejps.2023.106453. Epub 2023 May 4.

Abstract

Older adults are the main users of medicine and due to common multimorbidity they are often confronted with a complex medication management. This review article provides a brief overview on aspects of medication management, i.e., maintaining a stock of the required medicine, understanding and following the instructions for use, coping with the primary and secondary packaging, as well as the preparation prior to use. However, the main focus is on the drug intake itself and the review provides an overview of the current understanding of real life dosing conditions in older adults and geriatric patients. It elaborates the acceptability of dosage forms, in particular solid oral dosage forms as they represent the majority of dosage forms taken by this patient population. An improved understanding of the needs of older adults and geriatric patients, their acceptability of various dosage forms, and the circumstances under which they manage their medications will allow for the design of more patient-centric drug products.

Keywords: Geriatric patient; Intake condition; Medication management; Medicine acceptability; Older adult; Patient-centric.

Publication types

  • Review

MeSH terms

  • Aged
  • Dosage Forms*
  • Humans
  • Medication Review
  • Pharmaceutical Preparations* / administration & dosage

Substances

  • Dosage Forms
  • Pharmaceutical Preparations