Biogenic silver based nanostructures: Synthesis, mechanistic approach and biological applications

Environ Res. 2023 Aug 15;231(Pt 1):116045. doi: 10.1016/j.envres.2023.116045. Epub 2023 May 3.

Abstract

The alarming impact of antibiotic resistance sparked the quest for complementary treatments to overcome the confrontation over resistant pathogens. Metallic nanoparticles, especially silver nanoparticles (Ag NPs) have gained a much attention because of their remarkable biological characteristics. Moreover, their medicinal properties can be enhanced by preparing the composites with other materials. This article delves a comprehensive review of biosynthesis route for Ag NPs and their nanocomposites (NCs) with in-depth mechanism, methods and favorable experimental parameters. Comprehensive biological features Ag NPs such as antibacterial, antiviral, antifungal have been examined, with a focus on their potential uses in biomedicine and diagnostics has also been discussed. Additionally, we have also explored the hitches and potential outcomes of biosynthesis of Ag NPs in biomedical filed.

Keywords: AMR; Ag NPs; Anticancer; Antimicrobial; Biological synthesis; Biomedical.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents
  • Antiviral Agents
  • Metal Nanoparticles*
  • Nanocomposites*
  • Silver

Substances

  • Silver
  • Anti-Bacterial Agents
  • Antiviral Agents