Frontal Hypoperfusion and Cerebellar Hyperperfusion in Transient Alcoholic Cerebellar Degeneration

Clin Nucl Med. 2023 Jul 1;48(7):627-629. doi: 10.1097/RLU.0000000000004673. Epub 2023 May 5.

Abstract

A 55-year-old man consumed approximately 10 units of alcohol daily for 25 years, developing social withdrawal after retiring. For 2 months, he walked diagonally to the right, with a right shoulder droop. He spoke and walked slowly, but his speech was clear. After 20 days of abstinence, his symptoms improved, and his walk became more steady. Brain MRI revealed no specific finding. Brain perfusion scintigraphy with 99m Tc-ECD on 2-tailed view display in eZIS showed hypoperfusion in the prefrontal, frontal, and left anterior temporal lobes and left thalamus and hyperperfusion in the posterior white matter, parietal-occipital cortical regions, pons, and cerebellum.

Publication types

  • Case Reports

MeSH terms

  • Brain*
  • Cerebellum* / diagnostic imaging
  • Ethanol
  • Humans
  • Male
  • Middle Aged
  • Pons
  • Tomography, Emission-Computed, Single-Photon

Substances

  • Ethanol