A Case Report of Lung Transplantation After Hematopoietic Stem Cell Transplantation and Literature Review

Transplant Proc. 2023 Jun;55(5):1297-1301. doi: 10.1016/j.transproceed.2023.03.035. Epub 2023 May 2.

Abstract

Pulmonary complications may occur after hematopoietic stem cell transplantation for hematologic malignancies. Lung transplantation is the only treatment option for end-stage lung failure. We presented a case of acute myeloid leukemia who received a hematopoietic stem cell transplantation and underwent bilateral lung transplantation with end-stage usual interstitial pneumonia and chronic obstructive lung disease. This case showed that lung transplantation could be successfully applied in properly selected hematologic malignancy patients with long disease-free survival, like lung transplantations performed for other indications.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Graft vs Host Disease* / etiology
  • Hematologic Neoplasms* / therapy
  • Hematopoietic Stem Cell Transplantation* / adverse effects
  • Humans
  • Leukemia, Myeloid, Acute* / surgery
  • Lung Transplantation* / adverse effects
  • Transplantation, Homologous / adverse effects