Giant left atrial myxoma causing acute ischemic stroke

Future Cardiol. 2023 Mar;19(3):149-154. doi: 10.2217/fca-2022-0104. Epub 2023 May 4.

Abstract

Atrial myxomas are primary cardiac tumors which may cause ischemic stroke. The authors present a case of a 51-year-old man admitted to the emergency department with right-sided hemiplegia and aphasia caused by ischemic stroke. 2D and 3D transesophageal echocardiography showed an atrial myxoma described as a large mass in the left atrium attached to the interatrial septum. In the end, surgical excision of the myxoma was performed 48 h after diagnosis. Nowadays, specific guidelines concerning the correct time for surgical excision of the myxoma are lacking. The authors highlight the utmost role of echocardiography to promptly characterize a cardiac mass and the importance of discuss about the timing of cardiac surgery.

Keywords: atrial myxoma; cardiac surgery; ischemic stroke; transesophageal echocardiography.

Plain language summary

Atrial myxoma is a rare cardiac tumor that is often located in the left atrium of the heart. Patients with myxoma can have no symptoms, or they can present signs of systemic embolization, where fragments of the tumor have been released into the blood stream and are circulating to different areas of the body. Indeed, if a fragment reaches the brain, it can cause a cerebral acute ischemic stroke, which is a sudden loss of blood circulation to an area of the brain, resulting in a loss of neurologic function. Transesophageal echocardiography, an ultrasound test that produces real-time and detailed images of the heart, is a useful tool that allows physicians to diagnose the presence of an atrial myxoma. In this case report, the authors stress the role of echocardiography in diagnosing patients presenting with sudden neurological symptoms, because it can show a potential mass inside the heart. Once identified, the tumor can be removed surgically as soon as possible to avoid further complications, such as a new stroke.

Publication types

  • Case Reports

MeSH terms

  • Atrial Fibrillation* / complications
  • Echocardiography
  • Heart Atria / diagnostic imaging
  • Heart Atria / pathology
  • Heart Atria / surgery
  • Heart Neoplasms* / complications
  • Heart Neoplasms* / diagnosis
  • Heart Neoplasms* / surgery
  • Humans
  • Ischemic Stroke* / complications
  • Ischemic Stroke* / etiology
  • Male
  • Middle Aged
  • Myxoma* / complications
  • Myxoma* / diagnosis
  • Myxoma* / surgery
  • Stroke* / etiology