68Ga-FAPI-04 PET/MR Versus 18F-FDG PET/CT in the Detection of Ovarian Cancer

Clin Nucl Med. 2023 Jun 1;48(6):525-527. doi: 10.1097/RLU.0000000000004656.

Abstract

A 75-year-old woman presented with right lower abdominal pain. Pelvic ultrasound showed a cystic solid mass in the right adnexa. Painless enlarged lymph nodes on the left supraclavicular side with biopsy were suggestive of metastatic cancer. 18F-FDG PET/CT performed to evaluate the primary tumor showed intense uptake in both regions of the right adnexa and the gastric sinus, but 68Ga-FAPI PET/MRI showed uptake only in the right adnexal region. A subsequent gastroscopic biopsy confirmed atrophic inflammation. Finally, surgery histopathology revealed ovarian cancer. This case demonstrated that 68Ga-FAPI PET/MRI may help exclude suspected primary gastric carcinoma with false-positive 18F-FDG uptake.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Pain
  • Aged
  • Female
  • Fluorodeoxyglucose F18*
  • Humans
  • Ovarian Neoplasms* / diagnostic imaging
  • Positron Emission Tomography Computed Tomography

Substances

  • 68Ga-FAPI
  • Fluorodeoxyglucose F18