Economics of treatment with GnRH agonist 7-14 days after artificial insemination in repeat breeder lactating dairy cows

Reprod Domest Anim. 2023 Jul;58(7):929-934. doi: 10.1111/rda.14368. Epub 2023 May 9.

Abstract

This study looked at the effectiveness and financial benefits of treating repeat breeder (RB) dairy cows with the GnRH agonist gonadorelin 7-14 days after artificial insemination (AI). A total of 188 healthy dairy cows (2.4 ± 1.3 lactations) with an average milk yield of 42.1 ± 6.8 kg milk/day, at 179 ± 38.4 days in milk with 3.8 ± 1 AIs were divided into two groups, experimental (E group, n = 98) and control (C group, n = 90). The GnRH agonist gonadorelin was given 7-14 days after AI to the E group to evaluate the embryo survival in RB cows. The control group did not receive any treatment. Recorded pregnancy rates and cumulative pregnancy rates were superior in the E group (49% and 64.3%) compared with the C group (37.8% and 55.5%). The interaction between therapy and RB had a significant impact on the pregnancy rate and accessory corpus luteum (CL), according to a binary logistic regression study. The UW-DairyRepro$ decision support tool utilized in this experiment demonstrated that by implementing this approach, the net present value can be increased by US dollars (US$)30.2/RB cow/year. Thus, the single therapy with GnRH agonist gonadorelin between 7 and 14 days after AI enhanced the potential for a second CL in repeat-breeder pregnant cows, presumably favouring embryo survival.

Keywords: GnRH agonist; economic values; pregnancy rate; repeat breeder cows.

MeSH terms

  • Animals
  • Cattle
  • Corpus Luteum
  • Dinoprost
  • Estrus Synchronization
  • Female
  • Gonadotropin-Releasing Hormone*
  • Insemination, Artificial / veterinary
  • Lactation*
  • Pregnancy
  • Pregnancy Rate
  • Progesterone

Substances

  • Gonadotropin-Releasing Hormone
  • Dinoprost
  • Progesterone