Selective IgA2 deficiency in a patient with small intestinal Crohn's disease

J Clin Invest. 2023 Jun 15;133(12):e167742. doi: 10.1172/JCI167742.

Pablo Canales-Herrerias^{1

2}, Yolanda Garcia-Carmona¹, Joan Shang¹, Hadar Meringer^{1

2}, Debra S Yee³, Lin Radigan¹, Sofija Buta¹, Gustavo Martinez-Delgado^{1

2}, Michael Tankelevich^{1

2}, Drew Helmus², Marla Dubinsky², Annelie Everts-van der Mind⁴, Thierry Dervieux⁴, Dusan Bogunovic^{1

5}, Jean-Frederic Colombel^{1

2}, Jason M Brenchley³, Jeremiah Faith¹, Charlotte Cunningham-Rundles¹, Andrea Cerutti^{1

6

7}, Saurabh Mehandru^{1

2}

¹ Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
² Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
³ Barrier Immunity Section, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA.
⁴ Prometheus Laboratories, San Diego, California, USA.
⁵ Center for Inborn Errors of Immunity, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
⁶ Translational Clinical Research Program, Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain.
⁷ Catalan Institute for Research and Advanced Studies (ICREA), Barcelona, Spain.

No abstract available

Keywords: Adaptive immunity; Gastroenterology; Immunoglobulins; Immunology; Inflammatory bowel disease.

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