Wearable non-invasive glucose sensors based on metallic nanomaterials

Sheng Zhang; Wenjie Zhao; Junyan Zeng; Zhaotao He; Xiang Wang; Zehui Zhu; Runqing Hu; Chen Liu; Qianqian Wang

doi:10.1016/j.mtbio.2023.100638

Wearable non-invasive glucose sensors based on metallic nanomaterials

Mater Today Bio. 2023 Apr 15:20:100638. doi: 10.1016/j.mtbio.2023.100638. eCollection 2023 Jun.

Authors

Sheng Zhang^{1

2

3

4}, Wenjie Zhao^{1

2}, Junyan Zeng^{1

2}, Zhaotao He^{1

2}, Xiang Wang⁴, Zehui Zhu¹, Runqing Hu³, Chen Liu^{1

4}, Qianqian Wang^{1

3}

Affiliations

¹ Ningbo Innovation Center, Zhejiang University, Ningbo, 315100, China.
² School of Mechanical Engineering, Zhejiang University, Hangzhou, 310027, China.
³ NingboTech University, Ningbo, 315100, China.
⁴ Faculty of Science and Engineering, University of Nottingham Ningbo China, Ningbo, 315100, China.

Abstract

The development of wearable non-invasive glucose sensors provides a convenient technical means to monitor the glucose concentration of diabetes patients without discomfortability and risk of infection. Apart from enzymes as typical catalytic materials, the active catalytic materials of the glucose sensor are mainly composed of polymers, metals, alloys, metal compounds, and various metals that can undergo catalytic oxidation with glucose. Among them, metallic nanomaterials are the optimal materials applied in the field of wearable non-invasive glucose sensing due to good biocompatibility, large specific surface area, high catalytic activity, and strong adsorption capacity. This review summarizes the metallic nanomaterials used in wearable non-invasive glucose sensors including zero-dimensional (0D), one-dimensional (1D), and two-dimensional (2D) monometallic nanomaterials, bimetallic nanomaterials, metal oxide nanomaterials, etc. Besides, the applications of wearable non-invasive biosensors based on these metallic nanomaterials towards glucose detection are summarized in detail and the development trend of the wearable non-invasive glucose sensors based on metallic nanomaterials is also outlook.

Keywords: Electrochemical biosensor; Glucose sensor; Metallic nanomaterials; Non-invasive; Wearable sensor.

Publication types

Review