Atypical clinical features of post COVID-19 mucormycosis: A case series

Clin Exp Dent Res. 2023 Aug;9(4):623-629. doi: 10.1002/cre2.743. Epub 2023 May 1.

Abstract

Objectives: This case series aims to evaluate patients affected with post COVID-19 mucormycosis from clinical presentation to surgical and pharmacological treatment to improve the disease prognosis.

Material and methods: This case series was conducted at a specialized surgery hospital in Baghdad Medical City for over 10 months. Fifteen cases who had mild to severe COVID-19 infections followed by symptoms similar to aggressive periodontitis, such as mobility and bone resorption around the multiple maxillary teeth, were included in this case series.

Results: All patients did not receive COVID-19 vaccination; seven had a history of diabetes mellitus type 2, another five patients had a history of diabetes-like syndrome during the COVID-19 infection, and the remaining three patients had no history of any systemic diseases. No intracranial involvement was seen in all patients, and bilateral sinus involvement was seen in three patients.

Conclusion: Being highly suspicious of all patients affected with COVID-19 is highly recommended to avoid the complications of the late diagnosis of mucormycosis. In addition, our knowledge and methods in diagnosing and treating classical mucormycosis should be modified regarding post COVID-19 mucormycosis.

Keywords: COVID-19; diabetes mellitus; mucormycosis.

MeSH terms

  • Aggressive Periodontitis*
  • COVID-19 Vaccines
  • COVID-19*
  • Diabetes Mellitus, Type 2*
  • Humans
  • Mucormycosis* / diagnosis
  • Mucormycosis* / therapy

Substances

  • COVID-19 Vaccines