A label-free fiber ring laser biosensor for ultrahigh sensitivity detection of Salmonella Typhimurium

Shi Qiu; Bin Liu; Yuankui Leng; Edward Fox; Xian Zhou; Binbin Yan; Xinzhu Sang; Keping Long; Yanjun Fu; Xingdao He; Jinhui Yuan; Gerald Farrell; Qiang Wu

doi:10.1016/j.bios.2023.115337

A label-free fiber ring laser biosensor for ultrahigh sensitivity detection of Salmonella Typhimurium

Biosens Bioelectron. 2023 Aug 15:234:115337. doi: 10.1016/j.bios.2023.115337. Epub 2023 Apr 24.

Authors

Shi Qiu¹, Bin Liu², Yuankui Leng³, Edward Fox⁴, Xian Zhou⁵, Binbin Yan¹, Xinzhu Sang¹, Keping Long⁵, Yanjun Fu², Xingdao He², Jinhui Yuan⁶, Gerald Farrell⁷, Qiang Wu⁸

Affiliations

¹ State Key Laboratory of Information Photonics and Optical Communications, Beijing University of Posts and Telecommunications, Beijing, 100876, China.
² Key Laboratory of Optoelectronic Information Science and Technology of Jiangxi Province, Nanchang Hangkong University, Nanchang, 330063, China.
³ State Key Lab Food Sci & Technol, Nanchang University, Nanchang, China.
⁴ Faculty of Health and Life Sciences, Northumbria University, Newcastle Upon Tyne, NE1 8ST, United Kingdom.
⁵ Research Center for Convergence Networks and Ubiquitous Services, University of Science & Technology Beijing, Beijing, 100083, China.
⁶ State Key Laboratory of Information Photonics and Optical Communications, Beijing University of Posts and Telecommunications, Beijing, 100876, China; Research Center for Convergence Networks and Ubiquitous Services, University of Science & Technology Beijing, Beijing, 100083, China. Electronic address: yuanjinhui81@bupt.edu.cn.
⁷ Photonics Research Centre, School of Electrical and Electronic Engineering, City Campus, Technological University Dublin, Dublin 7, Ireland.
⁸ Key Laboratory of Optoelectronic Information Science and Technology of Jiangxi Province, Nanchang Hangkong University, Nanchang, 330063, China; Faculty of Engineering and Environment, Northumbria University, Newcastle Upon Tyne, NE1 8ST, United Kingdom. Electronic address: qiang.wu@northumbria.ac.uk.

PMID: 37126876
DOI: 10.1016/j.bios.2023.115337

Abstract

The rapid detection of low concentrations of Salmonella Typhimurium (S. Typhimurium) is an essential preventive measure for food safety and prevention of foodborne illness. The study presented in this paper addresses this critical issue by proposing a single mode-tapered seven core-single mode (STSS) fiber ring laser (FRL) biosensor for S. Typhimurium detection. The experimental results show that the specific detection time of S. Typhimurium is less than 20 min and the wavelength shift can achieve -0.906 nm for an S. Typhimurium solution (10 cells/mL). Furthermore, at a lower concentration of 1 cell/mL applied to the biosensor, a result of -0.183 nm is observed in 9% of samples (1/11), which indicates that the proposed FRL biosensor has the ability to detect 1 cell/mL of S. Typhimurium. In addition, the detection results in chicken and pickled pork samples present an average deviation of -27% and -23%, respectively, from the measured results in phosphate buffered saline. Taken together, these results show the proposed FRL biosensor may have potential applications in the fields of food safety monitoring, medical diagnostics, etc.

Keywords: Fiber ring laser biosensor; Foodborne pathogens; Salmonella Typhimurium (S. Typhimurium) detection.

MeSH terms

Biosensing Techniques* / methods
Food
Food Microbiology
Food Safety
Salmonella typhimurium