Dedifferentiated endometrial carcinoma arising from serous carcinoma: Diagnostic challenges and recommendations

Zhengfan Xu; Kasturi Saikia; Lisi Yuan

doi:10.1016/j.gore.2023.101188

Dedifferentiated endometrial carcinoma arising from serous carcinoma: Diagnostic challenges and recommendations

Gynecol Oncol Rep. 2023 Apr 13:47:101188. doi: 10.1016/j.gore.2023.101188. eCollection 2023 Jun.

Authors

Zhengfan Xu¹, Kasturi Saikia¹, Lisi Yuan¹

Affiliation

¹ Department of Pathology and Laboratory Medicine, Henry Ford Health System, Detroit, MI, USA.

Abstract

•Dedifferentiated endometrial carcinoma arising from serous carcinoma (null-type P53).•Differential diagnosis including carcinosarcoma, FIGO grade 3 endometrioid carcinoma.•Also need to rule out SMARCA4-deficient uterine sarcoma and other sarcomas.

Keywords: Dedifferentiated endometrial carcinoma; Null-type; P53; Serous carcinoma.

Publication types

Case Reports