Culturally safe, appropriate, and high-quality breast cancer screening for transgender people: A scoping review

Imogen Ramsey; Kate Kennedy; Greg Sharplin; Marion Eckert; Micah D J Peters

doi:10.1080/26895269.2022.2155289

Culturally safe, appropriate, and high-quality breast cancer screening for transgender people: A scoping review

Int J Transgend Health. 2023 Jan 13;24(2):174-194. doi: 10.1080/26895269.2022.2155289. eCollection 2023.

Authors

Imogen Ramsey¹, Kate Kennedy¹, Greg Sharplin¹, Marion Eckert¹, Micah D J Peters^{1

2

3}

Affiliations

¹ Rosemary Bryant AO Research Centre, Clinical & Health Sciences, University of South Australia, Adelaide, Australia.
² Faculty of Health and Medical Sciences, Adelaide Nursing School, The University of Adelaide, Adelaide, Australia.
³ The Centre for Evidence-based Practice South Australia (CEPSA): A JBI Centre of Excellence, Adelaide, Australia.

Abstract

Background: There is a recognized need for evidence to inform breast cancer screening guidelines and services for transgender people, who face barriers to accessing appropriate and inclusive health care.

Aims: This review summarized evidence for breast cancer risk and screening guidelines in transgender individuals, including the potential impact of gender-affirming hormone therapy (GAHT); factors that may influence screening decision-making and behaviors; and considerations for providing culturally safe, high-quality screening services.

Methods: A protocol was developed based on the Joanna Briggs Institute scoping review methodology. Searches were performed in Medline, Emcare, Embase, Scopus, and the Cochrane Library for articles reporting information on the provision of culturally safe, high-quality breast cancer screening services for transgender people.

Results: We identified 57 sources for inclusion: 13 cross-sectional studies, 6 case reports, 2 case series, 28 review or opinion articles, 6 systematic reviews, 1 qualitative study, and 1 book chapter. Evidence on rates of breast cancer screening among transgender people and the association between GAHT and breast cancer risk was inconclusive. Factors negatively associated with cancer screening behaviors included socioeconomic barriers, stigma, and lack of health provider awareness of transgender health issues. Breast cancer screening recommendations varied and were generally based on expert opinion due to the lack of clear evidence. Considerations for providing culturally safe care to transgender people were identified and mapped to the areas of workplace policies and procedures, patient information, clinic environment, professional conduct, communication, and knowledge and competency.

Discussion: Screening recommendations for transgender individuals are complicated by the lack of robust epidemiological data and clear understanding of the role GAHT may play in breast cancer pathogenesis. Guidelines have been developed based on expert opinion and are subsequently not uniform or evidence based. Further work is required to clarify and consolidate recommendations.

Keywords: Breast cancer; cultural safety; population health; prevention; screening; transgender.

Publication types

Review

Grants and funding

This study received funding from the Australian Government Department of Health, as part of a larger program of funded work. Specific funding was not quarantined for the development of the protocol and review. The funding source did not contribute to the writing of the manuscript.