Rheumatoid Arthritis from Easy to Complex Disease: From the "2022 GISEA International Symposium"

Simone Perniola; Maria Sole Chimenti; Francesca Romana Spinelli; Bruno Frediani; Rosario Foti; Sara Ferrigno; Cristina Garufi; Giulia Cassone; Vincenzo Venerito; Fabiola Atzeni; Roberto Caporali; Fabrizio Conti; Ennio Giulio Favalli; Florenzo Iannone; Marco Sebastiani; Gian Franco Ferraccioli; Giovanni Lapadula; Elisa Gremese

doi:10.3390/jcm12082781

Rheumatoid Arthritis from Easy to Complex Disease: From the "2022 GISEA International Symposium"

J Clin Med. 2023 Apr 9;12(8):2781. doi: 10.3390/jcm12082781.

Authors

Simone Perniola^{1

2}, Maria Sole Chimenti³, Francesca Romana Spinelli⁴, Bruno Frediani⁵, Rosario Foti⁶, Sara Ferrigno³, Cristina Garufi⁴, Giulia Cassone⁷, Vincenzo Venerito⁸, Fabiola Atzeni⁹, Roberto Caporali¹⁰, Fabrizio Conti⁴, Ennio Giulio Favalli^{10

11}, Florenzo Iannone⁸, Marco Sebastiani⁷, Gian Franco Ferraccioli¹, Giovanni Lapadula⁸, Elisa Gremese^{1

2}

Affiliations

¹ Immunology Research Core Facility, Gemelli Science and Technology Park (GSTeP), Fondazione Policlinico Universitario A. Gemelli IRCCS-Rome, 00168 Rome, Italy.
² Division of Clinical Immunology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore-Rome, 00168 Rome, Italy.
³ Rheumatology, Allergology and Clinical Immunology, Department of "Medicina dei Sistemi", University of Rome Tor Vergata, 00133 Rome, Italy.
⁴ Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari-Reumatologia, Sapienza Università di Roma, 00185 Rome, Italy.
⁵ Department of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
⁶ Rheumatology Unit, San Marco Hospital, Policlinico University of Catania, 95124 Catania, Italy.
⁷ Rheumatology Unit, Azienda Ospedaliera Policlinico di Modena, University of Modena and Reggio Emilia, 41121 Modena, Italy.
⁸ Department of Emergency and Organ Transplantation, Rheumatology Unit, University of Bari, 70121 Bari, Italy.
⁹ Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina, 98122 Messina, Italy.
¹⁰ Department of Rheumatology and Clinical Sciences, ASST Gaetano Pini-CTO, 20126 Milan, Italy.
¹¹ Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.

Abstract

Rheumatoid Arthritis (RA) is a systemic disease with many different clinical phenotypes. RA could be classified according to disease duration, seropositivity for rheumatoid factor (RF) and/or anti-citrullinated protein antibodies (ACPA), joint subtype, clinical behaviourbehavior and many other subgroups. In this review, we summarize and discuss the multifaceted aspects of RA, focusing on the relationship between autoimmunity status and clinical outcome, achievement of remission and influence on treatment response, from the 2022 International GISEA/OEG Symposium.

Keywords: remission; rheumatoid arthritis; seronegative; seropositive; therapy.

Publication types

Review

Grants and funding

This research received no external funding.