Olfaction: Allosteric modulation

Samuel Caton; Adam Dewan

doi:10.1016/j.cub.2023.03.046

Olfaction: Allosteric modulation

Curr Biol. 2023 Apr 24;33(8):R311-R313. doi: 10.1016/j.cub.2023.03.046.

Authors

Samuel Caton¹, Adam Dewan²

Affiliations

¹ Department of Psychology, Program in Neuroscience, Florida State University, Tallahassee, FL 32306, USA.
² Department of Psychology, Program in Neuroscience, Florida State University, Tallahassee, FL 32306, USA. Electronic address: dewan@psy.fsu.edu.

PMID: 37098335
DOI: 10.1016/j.cub.2023.03.046

Abstract

New research indicates that the odor-evoked responses of human olfactory receptors can be enhanced via the non-competitive binding of an allosteric modulator. This modulatory mechanism adds an additional layer of complexity to the peripheral encoding of odors.

Publication types

Comment

MeSH terms

Humans
Odorants
Olfactory Receptor Neurons* / physiology
Receptors, Odorant*
Smell / physiology

Substances

Receptors, Odorant