Imaging diagnostic features of intracranial primary extranodal Rosai-Dorfman disease: Two case reports and literature review

Gan Cao; Shanghuang Xie; Mifang Li; Xiaolin Yang; Jichao Zhu; Lingyan Zhang

doi:10.1016/j.radcr.2023.03.007

Imaging diagnostic features of intracranial primary extranodal Rosai-Dorfman disease: Two case reports and literature review

Radiol Case Rep. 2023 Apr 7;18(6):2165-2171. doi: 10.1016/j.radcr.2023.03.007. eCollection 2023 Jun.

Authors

Gan Cao¹, Shanghuang Xie¹, Mifang Li¹, Xiaolin Yang¹, Jichao Zhu¹, Lingyan Zhang¹

Affiliation

¹ Department of Medical Imaging, Longgang Central Hospital of Shenzhen, 6082 Longgang Avenue, Longgang District, Shenzhen, 518000, China.

Abstract

In this report, we describe 2 cases of rare intracranial extranodal Rosai-Dorfman disease. The occurrence of this type of non-Langerhans cell histiocytosis in the central nervous system is infrequent, with less than 5% of cases. The first patient was a 35-year-old male who presented with recurring headaches, and the second patient was a 50-year-old male who reported sudden onset of dizziness and vomiting. Computed tomography scans were performed in both cases, but magnetic resonance imaging played a crucial role in the characterization of the lesions and their locations in the thalamus, third ventricle, lateral ventricles, and cerebellopontine angle area. The final diagnosis was confirmed through pathological examination and immunohistochemistry following brain tumor resection. These cases underscore the significance of magnetic resonance imaging in the early diagnosis of intracranial extranodal Rosai-Dorfman disease.

Keywords: Case report; Computed tomography (CT); Magnetic resonance imaging (MRI); Meningioma; Rosai-Dorfman disease (RDD).

Publication types

Case Reports