Dual application of Polyvinyl Alcohol Glutaraldehyde Methylthymol Blue Fricke hydrogel in clinical practice: Surface dosimeter and bolus

Nooshin Sheykholeslami; Wrya Parwaie; Vahid Vaezzadeh; Mohammad Babaie; Mostafa Farzin; Ghazale Geraily; Amir Hossein Karimi

doi:10.1016/j.apradiso.2023.110827

Dual application of Polyvinyl Alcohol Glutaraldehyde Methylthymol Blue Fricke hydrogel in clinical practice: Surface dosimeter and bolus

Appl Radiat Isot. 2023 Jul:197:110827. doi: 10.1016/j.apradiso.2023.110827. Epub 2023 Apr 17.

Authors

Nooshin Sheykholeslami¹, Wrya Parwaie², Vahid Vaezzadeh³, Mohammad Babaie³, Mostafa Farzin⁴, Ghazale Geraily⁵, Amir Hossein Karimi⁶

Affiliations

¹ Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
² Department of Laboratory Sciences, School of Allied Medical Sciences, Ilam University of Medical Sciences, Iran.
³ Radiation Oncology Research Center, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
⁴ Brain and Spinal Cord Injury Research Center, Neuroscience Institute, Tehran University of Medical Science, Tehran, Iran.
⁵ Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Radiation Oncology Research Center, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: gh-geraily@sina.tums.ac.ir.
⁶ Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Radiation Oncology Research Center, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: amirhosseinkarimi.phd@gmail.com.

PMID: 37086713
DOI: 10.1016/j.apradiso.2023.110827

Abstract

An essential issue is an accurate evaluation of surface dose distribution for such sensitive treatments. This work aimed to feasibility of the dual application of the Ferrous Polyvinyl Alcohol Glutaraldehyde Methylthymol Blue (PVA-GTA-MTB) gel as a bolus compensator and surface dosimeter in breast radiotherapy. The differences between the surface dose measured using PVA-GTA-MTB gel and film dosimetry in the medial and lateral parts of the breast were 3.74% and 4.18%, respectively. A qualitative comparison of the isodose curves showed that the PVA-GTA-MTB bolus creates a uniform dose distribution similar to the superflab bolus in the target volume.

Keywords: Bolus; Dosimetry; Film; Gel; Monte Carlo; Radiotherapy.

MeSH terms

Glutaral
Hydrogels
Phantoms, Imaging
Polyvinyl Alcohol*
Radiation Dosimeters
Radiometry* / methods
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted / methods

Substances

polyvinyl alcohol hydrogel
Polyvinyl Alcohol
Glutaral
methylthymol blue
Hydrogels