Risk of hospitalization for self-harm among adults hospitalized with SARS-CoV-2 in France: A nationwide retrospective cohort study

Jean-Christophe Chauvet-Gelinier; Jonathan Cottenet; Matthieu Guillaume; Franck-Teddy Endomba; Fabrice Jollant; Catherine Quantin

doi:10.1016/j.psychres.2023.115214

Risk of hospitalization for self-harm among adults hospitalized with SARS-CoV-2 in France: A nationwide retrospective cohort study

Psychiatry Res. 2023 Jun:324:115214. doi: 10.1016/j.psychres.2023.115214. Epub 2023 Apr 15.

Authors

Jean-Christophe Chauvet-Gelinier¹, Jonathan Cottenet², Matthieu Guillaume³, Franck-Teddy Endomba³, Fabrice Jollant⁴, Catherine Quantin⁵

Affiliations

¹ Department of Psychiatry, Dijon University Hospital; INSERM Unit, LNC-UMR 1231, University of Burgundy, Dijon, France.
² Biostatistics and Bioinformatics (DIM), University Hospital, CHU Dijon Bourgogne, INSERM, Université de Bourgogne, CIC 1432, Module Épidémiologie Clinique, F21000 Dijon, France.
³ Department of Psychiatry, Dijon University Hospital.
⁴ Faculty of Medicine, Université Paris-Saclay, Le Kremlin-Bicêtre, France; Departement of psychiatry, CHU Bicêtre, APHP, Le Kremlin-Bicêtre, France; Department of psychiatry, CHU Nîmes, Nîmes, France; McGill Group for Suicide Studies, Department of psychiatry, McGill University, Montréal, QC, Canada.; Moods Research Team, INSERM UMR-1178, CESP, Le Kremlin-Bicêtre, France.
⁵ Biostatistics and Bioinformatics (DIM), University Hospital, CHU Dijon Bourgogne, INSERM, Université de Bourgogne, CIC 1432, Module Épidémiologie Clinique, F21000 Dijon, France; Université Paris-Saclay, UVSQ, Inserm, CESP, 94807, Villejuif, France. Electronic address: catherine.quantin@chu-dijon.fr.

Abstract

While much work has shown a link between the global SARS-CoV-2 pandemic and poor mental health, little is known about a possible association between hospitalization with SARS-CoV-2 infection and subsequent hospitalization for self-harm. Analyses performed on the French national hospital database between March 2020-March 2021 in 10,084,551 inpatients showed that hospitalization with SARS-CoV-2 infection was not associated with hospitalization for self-harm in the following year. However, hospitalization with SARS-Cov-2 was related to an increased risk of self-harm in patients with a suicidal episode at the inclusion (aHR=1.56[1.14-2.15]), suggesting an effect of SARS-CoV-2 in patients with a recent history of self-harm.

Keywords: COVID-19; Hospitalization; SARS-CoV-2; Self-harm.

MeSH terms

Adult
COVID-19*
Hospitalization
Humans
Retrospective Studies
SARS-CoV-2
Self-Injurious Behavior* / epidemiology