Different charge forms of aromatic-L-amino-acid decarboxylase

Brain Res. 1986 Apr 9;370(2):375-7. doi: 10.1016/0006-8993(86)90497-x.

Abstract

The isoelectric points (pI) of aromatic-L-amino-acid decarboxylase (AADC) from two species, rat and cow, were determined by chromatofocusing. The enzyme from both rat brain and adrenal has a pI of 5.5, while the bovine adrenal enzyme has a different pI of 5.0. Thus, the variation of isoelectric point for AADC is limited to species differences but not tissue differences.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adrenal Glands / enzymology*
  • Animals
  • Aromatic-L-Amino-Acid Decarboxylases / isolation & purification
  • Aromatic-L-Amino-Acid Decarboxylases / metabolism*
  • Brain / enzymology*
  • Cattle
  • Isoelectric Focusing
  • Isoenzymes / isolation & purification
  • Isoenzymes / metabolism*
  • Rats

Substances

  • Isoenzymes
  • Aromatic-L-Amino-Acid Decarboxylases