Plant-derived cross-kingdom gene regulation benefits human health

Yongmei Li; Zhaowei Teng; Dake Zhao

doi:10.1016/j.tplants.2023.03.004

Plant-derived cross-kingdom gene regulation benefits human health

Trends Plant Sci. 2023 Jun;28(6):626-629. doi: 10.1016/j.tplants.2023.03.004. Epub 2023 Apr 18.

Authors

Yongmei Li¹, Zhaowei Teng², Dake Zhao³

Affiliations

¹ School of Ecology and Environmental Science, Yunnan University, Kunming, 650504, China.
² The Central Laboratory and Department of orthopedic, The Second Affiliated Hospital of Kunming Medical University, Kunming, 650106, China; Clinical Medical Research Center and Key Laboratory of Yunnan Provincial Innovative Application of Traditional Chinese Medicine, The First People's Hospital of Yunnan Province, Affiliated Hospital of Kunming University of Science and Technology, Kunming, 650034, China.
³ School of Ecology and Environmental Science, Yunnan University, Kunming, 650504, China. Electronic address: zhaodk2012@ynu.edu.cn.

PMID: 37080836
DOI: 10.1016/j.tplants.2023.03.004

Abstract

Cross-kingdom gene regulation widely occurs in nature through small (s)RNAs or protein-encoding genes. Examples of plant-derived miRNAs that are advantageous for human health have recently been reported. Mining plant-specialized gene resources for similar cross-kingdom gene communications may lead to the identification of further plant-derived therapeutic agents that can improve human health globally.

Keywords: cross-kingdom gene regulation; human health; miRNA; plant gene resources.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Gene Expression Regulation, Plant / genetics
Humans
MicroRNAs* / genetics
Plants / genetics
RNA, Plant / genetics

Substances

MicroRNAs
RNA, Plant