1 Department of Intensive Care Medicine, Center for Critical Care, Computation Intelligence (C4i), Amsterdam Medical Data Science (AMDS), Amsterdam Public Health (APH), Amsterdam Cardiovascular Science (ACS), Amsterdam Institute for Infection and Immunity (AII), Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands. a.janssen@amsterdamumc.nl.
2 Department of Clinical Pharmacology, Hospital Pharmacy, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands. a.janssen@amsterdamumc.nl.
3 Department of Intensive Care Medicine, Ghent University Hospital, Ghent, Belgium.
4 Department of Internal Medicine and Paediatrics, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
5 Department of Intensive Care Medicine, Center for Critical Care, Computation Intelligence (C4i), Amsterdam Medical Data Science (AMDS), Amsterdam Public Health (APH), Amsterdam Cardiovascular Science (ACS), Amsterdam Institute for Infection and Immunity (AII), Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.