1 Department of Clinical and Experimental Medicine and Pharmacology, Section of Pharmacology, University of Messina, Via C. Valeria Gazzi, 98125, Messina, Italy.
2 Department of Neurosciences, Psychiatry and Anaesthesiology, University of Messina, Via C. Valeria Gazzi, 98125, Messina, Italy.
3 Department of Clinical and Experimental Medicine and Pharmacology, Section of Pharmacology, University of Messina, Via C. Valeria Gazzi, 98125, Messina, Italy. Francesco.Squadrito@unime.it.