Brief mock-scan training reduces head motion during real scanning for children: A growth curve study

Peng Gao; Yin-Shan Wang; Qiu-Yu Lu; Meng-Jie Rong; Xue-Ru Fan; Avram J Holmes; Hao-Ming Dong; Hai-Fang Li; Xi-Nian Zuo

doi:10.1016/j.dcn.2023.101244

Brief mock-scan training reduces head motion during real scanning for children: A growth curve study

Dev Cogn Neurosci. 2023 Jun:61:101244. doi: 10.1016/j.dcn.2023.101244. Epub 2023 Apr 13.

Authors

Peng Gao¹, Yin-Shan Wang², Qiu-Yu Lu², Meng-Jie Rong³, Xue-Ru Fan⁴, Avram J Holmes⁵, Hao-Ming Dong⁶, Hai-Fang Li⁷, Xi-Nian Zuo⁸

Affiliations

¹ College of Information and Computer, Taiyuan University of Technology, No. 79 West Street Yingze, Taiyuan, Shanxi 030024, China.
² State Key Laboratory of Cognitive Neuroscience and Learning, Faculty of Psychology, Beijing Normal University, No 19 Xinjiekouwai Street, Haidian District, Beijing 100875, China; Developmental Population Neuroscience Research Center, IDG/McGovern Institute for Brain Research, Beijing Normal University, No 19 Xinjiekouwai Street, Haidian District, Beijing 100875, China.
³ State Key Laboratory of Cognitive Neuroscience and Learning, Faculty of Psychology, Beijing Normal University, No 19 Xinjiekouwai Street, Haidian District, Beijing 100875, China; Institute of Psychology, Chinese Academy of Sciences, No 16 Lincui Road, Chaoyang District, Beijing 100101, China.
⁴ State Key Laboratory of Cognitive Neuroscience and Learning, Faculty of Psychology, Beijing Normal University, No 19 Xinjiekouwai Street, Haidian District, Beijing 100875, China; Developmental Population Neuroscience Research Center, IDG/McGovern Institute for Brain Research, Beijing Normal University, No 19 Xinjiekouwai Street, Haidian District, Beijing 100875, China; Institute of Psychology, Chinese Academy of Sciences, No 16 Lincui Road, Chaoyang District, Beijing 100101, China.
⁵ Department of Psychology, Yale University, 1 Prospect Street, New Haven, CT 06511, USA.
⁶ State Key Laboratory of Cognitive Neuroscience and Learning, Faculty of Psychology, Beijing Normal University, No 19 Xinjiekouwai Street, Haidian District, Beijing 100875, China; Developmental Population Neuroscience Research Center, IDG/McGovern Institute for Brain Research, Beijing Normal University, No 19 Xinjiekouwai Street, Haidian District, Beijing 100875, China. Electronic address: donghaomingnd@gmail.com.
⁷ College of Information and Computer, Taiyuan University of Technology, No. 79 West Street Yingze, Taiyuan, Shanxi 030024, China. Electronic address: lihaifang@tyut.edu.cn.
⁸ State Key Laboratory of Cognitive Neuroscience and Learning, Faculty of Psychology, Beijing Normal University, No 19 Xinjiekouwai Street, Haidian District, Beijing 100875, China; Developmental Population Neuroscience Research Center, IDG/McGovern Institute for Brain Research, Beijing Normal University, No 19 Xinjiekouwai Street, Haidian District, Beijing 100875, China; Institute of Psychology, Chinese Academy of Sciences, No 16 Lincui Road, Chaoyang District, Beijing 100101, China; National Basic Science Data Center, No 2 Dongsheng South Road, Haidian District, Beijing 100190, China. Electronic address: xinian.zuo@bnu.edu.cn.

Abstract

Pediatric neuroimaging datasets are rapidly increasing in scales. Despite strict protocols in data collection and preprocessing focused on improving data quality, the presence of head motion still impedes our understanding of neurodevelopmental mechanisms. Large head motion can lead to severe noise and artifacts in magnetic resonance imaging (MRI) studies, inflating correlations between adjacent brain areas and decreasing correlations between spatial distant territories, especially in children and adolescents. Here, by leveraging mock-scans of 123 Chinese children and adolescents, we demonstrated the presence of increased head motion in younger participants. Critically, a 5.5-minute training session in an MRI mock scanner was found to effectively suppress the head motion in the children and adolescents. Therefore, we suggest that mock scanner training should be part of the quality assurance routine prior to formal MRI data collection, particularly in large-scale population-level neuroimaging initiatives for pediatrics.

Keywords: growth curve; head motion; mock scan; neurodevelopment; pediatric chart; quality control; resting-state fMRI.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Artifacts
Brain* / diagnostic imaging
Child
Head Movements
Humans
Magnetic Resonance Imaging* / methods
Motion
Neuroimaging