PROTOCOL: The association between whole-grain dietary intake and noncommunicable diseases: A systematic review and meta-analysis

Wasim A Iqbal; Gavin B Stewart; Abigail Smith; Linda Errington; Chris J Seal

doi:10.1002/cl2.1186

PROTOCOL: The association between whole-grain dietary intake and noncommunicable diseases: A systematic review and meta-analysis

Campbell Syst Rev. 2021 Jul 26;17(3):e1186. doi: 10.1002/cl2.1186. eCollection 2021 Sep.

Authors

Wasim A Iqbal¹, Gavin B Stewart¹, Abigail Smith¹, Linda Errington¹, Chris J Seal¹

Affiliation

¹ Newcastle University Newcastle upon Tyne UK.

Abstract

Our primary research questions are: (1) What is the association between whole grains (WG) intake and the prevalence of NCDs (i.e., type 2 diabetes, cardiovascular disease, obesity, cancer, mortality) and their biomarkers? (2) Which biomarker(s) has/have the greatest association with WG intake when combining multiple biomarkers together in the same analysis? Our secondary research question is: (3) Are there dose-response relationships between WG intake and biomarkers and prevalence of NCDs which could help inform a universal recommendation for WG intake?