Equine Gastric Ulcer Syndrome: An Update on Current Knowledge

Animals (Basel). 2023 Apr 5;13(7):1261. doi: 10.3390/ani13071261.

Abstract

Equine Gastric Ulcer Syndrome (EGUS) is a term that has been used since 1999, initially being used to describe all gastric mucosal disease in horses. Since this time, the identification of two distinct main disease entities of the equine gastric mucosa have been described under the umbrella of EGUS; these are Equine Squamous Gastric Disease (ESGD) and Equine Glandular Gastric Disease (EGGD). In 2015 the European College of Equine Internal Medicine (ECEIM) released a consensus statement defining these disease entities. This document highlighted the lack of evidence surrounding EGGD compared to ESGD, and identified knowledge gaps for further research to be directed. Subsequently, many studies on EGGD have been published, especially on pathophysiology, diagnosis, and treatment. This article updates current knowledge on both ESGD and EGGD as understanding has evolved since the last large-scale review.

Keywords: Equine Glandular Gastric Disease; Equine Squamous Gastric Disease; horse; misoprostol; omeprazole; stomach; sucralfate.

Publication types

  • Review

Grants and funding

This research received no external funding.