Synthesis of Graphene Quantum Dot Magnesium Hydroxide Nanocomposites and Investigation of Their Antioxidant and Antimicrobial Activities

Curr Microbiol. 2023 Apr 12;80(5):181. doi: 10.1007/s00284-023-03286-0.

Abstract

In this paper, we synthesized graphene quantum dots magnesium hydroxide nanocomposites (GQDs/Mg(OH)2). The synthesized nanocomposites were characterized by UV-Vis spectroscopy, X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), and Malvern Zetasizer. The antimicrobial and antioxidant properties of the obtained GQDs/Mg(OH)2 nanocomposites were investigated. GQDs/Mg(OH)2 nanocomposites have MIC values of 15.625 μg/mL against fungi (C. metapsilosis and C. parapsilosis) and 62.5 μg/mL against Gram (+) (S. pneumonia and E. faecalis) and Gram (-) (E. coli). The synthesized GQDs/Mg(OH)2 nanocomposites showed moderate antioxidant activity. The results showed that at 100-µg/mL GQDs/Mg(OH)2 nanocomposite concentration, the H2O2 scavenging activity was 62.18%.

MeSH terms

  • Anti-Infective Agents* / pharmacology
  • Antioxidants / pharmacology
  • Escherichia coli
  • Graphite* / chemistry
  • Graphite* / pharmacology
  • Hydrogen Peroxide / pharmacology
  • Magnesium Hydroxide
  • Nanocomposites* / chemistry
  • Quantum Dots* / chemistry

Substances

  • Antioxidants
  • Graphite
  • Magnesium Hydroxide
  • Hydrogen Peroxide
  • Anti-Infective Agents