Estimation of postmortem interval (PMI) is one of the important research contents in forensic pathology, and it has always been the focus and hot spot of research work. In recent years, scholars at home and abroad have made some research progress in estimating PMI by using ocular tissue. After death, the changes of cornea, aqueous humor, iris, lens, vitreous humor and retina all show time sequence change rule highly related to PMI. This paper reviews the research progress of PMI estimation based on the morphological, biochemical, molecular and genetic material changes of different ocular tissue structures after death, and discusses the existing problems and development trends.
死亡时间（postmortem interval，PMI）推断是法医病理学研究的重点与热点问题。近年来，国内外学者利用眼组织推断PMI取得了一定进展，机体死后眼角膜、房水、虹膜、晶状体、玻璃体液、视网膜等改变均呈现与PMI高度相关的时序性变化规律。本文基于眼组织不同结构死后形态学、生物化学、分子学、遗传物质改变等方面，对PMI推断研究进展进行了综述，对存在的问题及发展趋势进行探讨。.
Keywords: cornea; forensic pathology; ocular tissues; postmortem interval; review; vitreous humor.