Current Management Options for Dyspnea in Cancer Patients

Curr Treat Options Oncol. 2023 Jun;24(6):565-579. doi: 10.1007/s11864-023-01081-4. Epub 2023 Apr 11.

Abstract

Dyspnea is one of the most frequent and distressing symptoms in patients with advanced cancer. As dyspnea deteriorates patients' quality of life markedly and tends to worsen as the disease progresses, comprehensive assessment and timely treatment of the underlying etiologies are essential. International guidelines recommend various non-pharmacological and pharmacological management options. However, there is a scarcity of confirmatory clinical trials on cancer dyspnea, and the overall level of evidence is weak. Recently, observational and survey studies indicated a wide range of practice patterns of palliative care specialists, providing important insight into the real-world management of dyspnea. In this paper, we summarize current management options for dyspnea in cancer patients, highlight major controversies in the literature, and propose future research directions toward quality care for patients with dyspnea and their families.

Keywords: Care; Dyspnea; Etiology; Pharmacological management.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Dyspnea / diagnosis
  • Dyspnea / etiology
  • Dyspnea / therapy
  • Humans
  • Neoplasms* / complications
  • Neoplasms* / therapy
  • Palliative Care
  • Quality of Life*