Green synthesis of MgO nanoparticles and its antibacterial properties

Rajeshwari B Rotti; D V Sunitha; Ramya Manjunath; Arpita Roy; Shilpa Borehalli Mayegowda; A P Gnanaprakash; Saad Alghamdi; Mazen Almehmadi; Osama Abdulaziz; Mamdouh Allahyani; Abdulelah Aljuaid; Ahad Amer Alsaiari; Sami S Ashgar; Ahmad O Babalghith; Amal Ezzat Abd El-Lateef; Elshiekh B Khidir

doi:10.3389/fchem.2023.1143614

Green synthesis of MgO nanoparticles and its antibacterial properties

Front Chem. 2023 Mar 23:11:1143614. doi: 10.3389/fchem.2023.1143614. eCollection 2023.

Authors

Rajeshwari B Rotti¹, D V Sunitha¹, Ramya Manjunath², Arpita Roy³, Shilpa Borehalli Mayegowda⁴, A P Gnanaprakash⁵, Saad Alghamdi⁶, Mazen Almehmadi⁷, Osama Abdulaziz⁷, Mamdouh Allahyani⁷, Abdulelah Aljuaid⁷, Ahad Amer Alsaiari⁷, Sami S Ashgar⁸, Ahmad O Babalghith⁹, Amal Ezzat Abd El-Lateef⁶, Elshiekh B Khidir⁶

Affiliations

¹ Department of Physics, School of Applied Sciences, REVA University, Bangalore, India.
² Department of Biotechnology, School of Applied Sciences, REVA University, Bangalore, India.
³ Department of Biotechnology, Sharda School of Engineering and Technology, Sharda University, Greater Noida, India.
⁴ CHRIST-Deemed to be University, Kengeri Campus, Bangalore, Karnataka, India.
⁵ Department of Studies in Physics, University of Mysore, Mysuru, India.
⁶ Laboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
⁷ Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia.
⁸ Department of Microbiology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.
⁹ Medical Genetics Department, College of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.

Abstract

Magnesium oxide nanostructured particles (NP) were prepared using a simple solution combustion technique using different leaf extracts such as Mangifera indica (Mango - Ma), Azadirachta indica (Neem-Ne), and Carica papaya (Papaya-Pa) as surfactants. The highly crystalline phase of MgO nanostructures was confirmed by PXRD and FTIR studies for 2 h 500°C calcined samples. To analyze the characteristics of obtained material-MaNP, NeNP, and PaNP for dosimetry applications, thermoluminescence (TL) studies were carried out for Co-60 gamma rays irradiated samples in the dose range 10-50 KGy; PaNP and NeNP exhibited well-defined glow curve when compared with MaNP samples. In addition, it was observed that the TL intensity decreases, with increase in gamma dose and the glow peak temperature is shifted towards the higher temperature with the increase in heating rate. The glow peak was segregated using glow curve deconvolution and thermal cleaning method. Kinetic parameters estimated using Chen's method, trap depth (E), and frequency factor (s) were found to be 0.699, 7.408, 0.4929, and 38.71, 11.008, and 10.71 for PaNP, NeNP, and MaNP respectively. The well-resolved glow curve, good linear behavior in the dose range of 10-50, KGy, and less fading were observed in PaNP as compared with MaNP and NeNP. Further, the antibacterial activity was checked against human pathogens such as Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa. A visible zone of clearance was observed at 200 and 100 μg/mL by the PaNP and NeNP, indicating the death of colonies by the nanoparticles. Therefore, PaNP nanomaterial is a potential phosphor material for dosimetry and antibacterial application compared to NeNP and MaNP.

Keywords: anti-bacterial activity; defects; dosimetry; green synthesis; thermoluminescence.

Grants and funding

The work was funded by the Seed money fund granted by REVA University.