OXA-48 Carbapenemase-Producing Salmonella typhimurium Nosocomial Bacteremia in the Intensive Care Unit: A Case Report and Review of the Literature

Cureus. 2023 Mar 6;15(3):e35811. doi: 10.7759/cureus.35811. eCollection 2023 Mar.

Abstract

Salmonella enterica serovar Typhimurium is a gram-negative bacterium mainly involved in foodborne diseases. Several pathways of antimicrobial resistance have been recently identified in this strain. This article reports a case of a patient hospitalized in intensive care who underwent emergency trauma surgery. During his hospitalization, he developed a nosocomial bacteremia from a surgical wound infection. The cytobacteriological examination of the surgical site and the blood culture isolated Salmonella spp. susceptible to third-generation cephalosporins, resistant to ertapenem, and with decreased sensitivity to imipenem. The carbapenemase test was positive for blaOXA-48. The serotyping identified Salmonella enterica serovar Typhimurium. The patient's response to antibiotics was favorable.

Keywords: bacteremia; blaoxa-48; carbapenemase; intensive care unit; nosocomial infection; salmonella typhimurium; surgical wound infection.

Publication types

  • Case Reports