Beyond squamous cell carcinoma: MRI appearance of uncommon anal neoplasms and mimickers

Abdom Radiol (NY). 2023 Sep;48(9):2898-2912. doi: 10.1007/s00261-023-03891-4. Epub 2023 Apr 7.

Abstract

Anal cancer is an uncommon malignancy. In addition to squamous cell carcinoma, there are a variety of other less common malignancies and benign pathologies that may afflict the anal canal, with which abdominal radiologists should be familiar. Abdominal radiologists should be familiar with the imaging features that can help distinguish different rare anal tumors beyond squamous cell carcinoma and that can aid in diagnosis therefore help steer management. This review discusses these uncommon pathologies with a focus on their imaging appearance, management, and prognosis.

Keywords: Adenocarcinoma; Anal cancer; Gastrointestinal stromal tumors; Lymphoma; Magnetic resonance imaging; Melanoma.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • Anal Canal
  • Anus Neoplasms* / diagnostic imaging
  • Anus Neoplasms* / pathology
  • Carcinoma, Squamous Cell* / diagnostic imaging
  • Carcinoma, Squamous Cell* / pathology
  • Humans
  • Magnetic Resonance Imaging
  • Prognosis