Liver transplantation for alcohol-associated liver disease: A call for national standards of best practices to monitor and bridge disparities in access and outcomes

Am J Transplant. 2023 Aug;23(8):1097-1101. doi: 10.1016/j.ajt.2023.03.026. Epub 2023 Apr 5.

Abstract

Early (ie, without a mandated abstinence period) liver transplantation for alcohol-associated liver disease is the fastest-growing indication for liver transplantation in the United States. Despite widespread adoption, there is no standardization of practice or policies across transplant centers, nor are there any quality metrics from regulatory organizations specific to alcohol, all of which have likely contributed to confirmed disparities in transplant access and patient outcomes. In this article, we propose new mandates and best practices that could be put forth by the organ procurement and transplantation network regarding processes related to candidate selection, monitoring of alcohol use, and services to prevent and treat harmful alcohol use among early transplant candidates and recipients. We hope that this article stimulates discussion and leads to policy changes to maximize equity and quality of transplant care.

Keywords: Audit; Disparities; OPTN; Policy; UNOS.

MeSH terms

  • Humans
  • Liver Diseases*
  • Liver Transplantation*
  • Tissue and Organ Procurement*
  • Transplants*
  • United States
  • Waiting Lists