The Risk of P-Glycoprotein-Mediated Drug-Drug Interaction May Also Depend on The Vulnerability of The Victim Substrate to Partial Inhibition

J Pharm Sci. 2023 Jul;112(7):2005. doi: 10.1016/j.xphs.2023.03.023. Epub 2023 Apr 4.

Authors

Louise Breuil¹, Solène Marie¹, Nicolas Tournier²

Affiliations

¹ Laboratoire d'Imagerie Biomédicale Multimodale (BioMaps), CEA, CNRS, Inserm, Service Hospitalier Frédéric Joliot, Université Paris-Saclay, Orsay, France.
² Laboratoire d'Imagerie Biomédicale Multimodale (BioMaps), CEA, CNRS, Inserm, Service Hospitalier Frédéric Joliot, Université Paris-Saclay, Orsay, France. Electronic address: nicolas.tournier@cea.fr.

PMID: 37023854
DOI: 10.1016/j.xphs.2023.03.023

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

ATP Binding Cassette Transporter, Subfamily B
ATP Binding Cassette Transporter, Subfamily B, Member 1*
Drug Interactions

Substances

ATP Binding Cassette Transporter, Subfamily B, Member 1
ATP Binding Cassette Transporter, Subfamily B