Vesiculobullous Lesions of the Oral Cavity

Saja A Alramadhan; Mohammed N Islam

doi:10.1016/j.coms.2022.10.006

Vesiculobullous Lesions of the Oral Cavity

Oral Maxillofac Surg Clin North Am. 2023 May;35(2):203-217. doi: 10.1016/j.coms.2022.10.006.

Authors

Saja A Alramadhan¹, Mohammed N Islam²

Affiliations

¹ Department of Oral and Maxillofacial Diagnostic Sciences, University of Florida College of Dentistry, 1395 Center Drive, Room D8-06, Gainesville, FL 32610, USA. Electronic address: salramadhan@dental.ufl.edu.
² Department of Oral and Maxillofacial Diagnostic Sciences, University of Florida College of Dentistry, 1395 Center Drive, Room D8-06, Gainesville, FL 32610, USA.

PMID: 37019505
DOI: 10.1016/j.coms.2022.10.006

Abstract

Several dermatological conditions may manifest in the oral cavity, particularly those that are immune-mediated, and they must be distinguished from the various other types of oral ulcerations. This chapter discusses the clinical features, pathogenesis, differential diagnosis, and diagnostic features, including histology and immunofluorescence findings, as well as management of vesiculobullous diseases. These diseases include pemphigus Vulgaris, benign mucous membrane pemphigoid, bullous pemphigoid, and epidermolysis bullosa acquisita. These diseases have a significant impact on the quality of life, as they can lead to serious complications, depending on the extent of the disease. Therefore, early recognition is crucial, helping to reduce disease-related morbidity, mortality and prevent life-threatening complications.

Keywords: Bullous pemphigoid; Cicatricial pemphigoid; Desquamative gingivitis; Epidermolysis bullosa acquisita; Pemphigus vulgaris.

Publication types

Review

MeSH terms

Epidermolysis Bullosa Acquisita* / diagnosis
Epidermolysis Bullosa Acquisita* / pathology
Humans
Mouth / pathology
Pemphigoid, Benign Mucous Membrane* / diagnosis
Pemphigoid, Bullous* / diagnosis
Pemphigoid, Bullous* / pathology
Quality of Life