1 Anesthesia and Intensive Care, IRCCS Policlinico San Martino, Genoa, Italy. kiarobba@gmail.com.
2 Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Viale Benedetto XV 16, Genoa, Italy. kiarobba@gmail.com.
3 Department of Adult Critical Care, Guy's and St Thomas' NHS Foundation Trust, London, UK.
4 Centre for Human and Applied Physiological Sciences, School of Basic and Medical Biosciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.
5 School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.