Relapsing Encephalomyelitis After COVID-19 Infection and Vaccination: From the National MS Society Case Conference Proceedings

Shuvro Roy; Paula Barreras; Carlos A Pardo; Jennifer S Graves; Scott S Zamvil; Scott D Newsome

doi:10.1212/NXI.0000000000200112

Relapsing Encephalomyelitis After COVID-19 Infection and Vaccination: From the National MS Society Case Conference Proceedings

Neurol Neuroimmunol Neuroinflamm. 2023 Apr 4;10(3):e200112. doi: 10.1212/NXI.0000000000200112. Print 2023 May.

Authors

Shuvro Roy¹, Paula Barreras¹, Carlos A Pardo¹, Jennifer S Graves¹, Scott S Zamvil¹, Scott D Newsome²

Affiliations

¹ From the Department of Neurology (S.R., P.B., C.A.P., S.D.N.), Johns Hopkins School of Medicine; Department of Neurology (J.S.G.), University of California San Diego School of Medicine; and Department of Neurology (S.S.Z.), University of California San Francisco School of Medicine.
² From the Department of Neurology (S.R., P.B., C.A.P., S.D.N.), Johns Hopkins School of Medicine; Department of Neurology (J.S.G.), University of California San Diego School of Medicine; and Department of Neurology (S.S.Z.), University of California San Francisco School of Medicine. snewsom2@jhmi.edu.

Abstract

Prior case studies suggest that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its vaccines may unmask CNS neuroinflammatory conditions. We present a case of relapsing steroid-responsive encephalomyelitis after SARS-CoV-2 infection and subsequent COVID-19 vaccination. We also characterize the frequency of CNS neuroinflammatory events reported in the literature after both SARS-CoV-2 infection and COVID-19 vaccination.

Publication types

Case Reports

MeSH terms

COVID-19 Vaccines* / adverse effects
COVID-19* / prevention & control
Encephalomyelitis* / diagnosis
Humans
SARS-CoV-2
Vaccination / adverse effects

Substances

COVID-19 Vaccines