Inhibition of ALDH2 by disulfiram leads to synthetic lethality via ROS strikes twice in ARID1A-deficient cholangiocarcinoma

Genes Dis. 2022 Mar 16;10(1):69-71. doi: 10.1016/j.gendis.2022.02.005. eCollection 2023 Jan.

¹ Jiangsu Key Laboratory for Molecular and Medical Biotechnology, School of Life Science, Nanjing Normal University, Nanjing, Jiangsu 210023, China.
² Department of Bioinformatics, Smart Health Big Data Analysis and Location Services Engineering Lab of Jiangsu Province, School of Geographic and Biologic Information, Nanjing University of Posts and Telecommunications, Nanjing, Jiangsu 210023, China.

No abstract available