A Case Report of Acute Severe Necrotizing Pancreatitis following the Johnson & Johnson Vaccine against the Novel SARS-CoV-2

Ayrton I Bangolo; Mahabuba Akhter; Auda Auda; Rahina Akram; Vignesh K Nagesh; Donnee Athem; Reenu Thomas; Ligaya Tibalan; Mansi Trivedi; Saima Mushtaq; Neha Singh; Pracheta Bagale; Georgemar V Arana Jr; Tayyaba Khan; Shelja Sharma; Swetha Mynedi; Dhara D Patel; Mandeep Saini; Madhurya R Chinthakuntla; Kareem Ahmed; Mary Gad; Srikara Dheer D R Gondhi; Georgemar Arana; Rohini B Gurumoorthy; Simcha Weissman

doi:10.1155/2023/9965435

A Case Report of Acute Severe Necrotizing Pancreatitis following the Johnson & Johnson Vaccine against the Novel SARS-CoV-2

Case Rep Infect Dis. 2023 Mar 22:2023:9965435. doi: 10.1155/2023/9965435. eCollection 2023.

Authors

Ayrton I Bangolo¹, Mahabuba Akhter¹, Auda Auda¹, Rahina Akram¹, Vignesh K Nagesh¹, Donnee Athem¹, Reenu Thomas¹, Ligaya Tibalan¹, Mansi Trivedi¹, Saima Mushtaq¹, Neha Singh¹, Pracheta Bagale¹, Georgemar V Arana Jr¹, Tayyaba Khan¹, Shelja Sharma¹, Swetha Mynedi¹, Dhara D Patel¹, Mandeep Saini¹, Madhurya R Chinthakuntla¹, Kareem Ahmed², Mary Gad¹, Srikara Dheer D R Gondhi¹, Georgemar Arana¹, Rohini B Gurumoorthy¹, Simcha Weissman¹

Affiliations

¹ Department of Internal Medicine, Palisades Medical Center, North Bergen, NJ, USA.
² Department of Internal Medicine, University of Washington, Seattle, Washington, USA.

Abstract

Acute pancreatitis is an inflammatory condition, which is a leading gastrointestinal cause of hospitalization in the United States. Several conditions are associated with acute pancreatitis. More recently, there have been a few cases reported of acute pancreatitis following the Pfizer-BioNTech COVID-19 mRNA vaccine. To our knowledge, no cases of acute pancreatitis have been yet reported following the Johnson & Johnson's Janssen COVID-19 vaccine (J& J vaccine). Herein we report a 34-year-old male with no significant past medical history admitted with acute necrotizing pancreatitis, the day following the receipt of the J&J vaccine. Based on the Naranjo and the modified Naranjo scale, the patient met the requirements for probable drug induced pancreatitis. This case report has the objective to raise awareness of a potentially severe side effect of the J&J vaccine. We hope to use this case to support screening all patients for previous history of acute pancreatitis before administration of the J& J vaccine.

Publication types

Case Reports