Vitreoretinal Lymphoma as the Initial Presentation of a Breast Diffuse Large B-cell Lymphoma

Cole A Martin; Joan H Admirand; Shelley Day Ghafoori

doi:10.1177/24741264211034162

Vitreoretinal Lymphoma as the Initial Presentation of a Breast Diffuse Large B-cell Lymphoma

J Vitreoretin Dis. 2021 Nov 2;6(5):414-418. doi: 10.1177/24741264211034162. eCollection 2022 Sep-Oct.

Authors

Cole A Martin¹, Joan H Admirand¹, Shelley Day Ghafoori^{1

2}

Affiliations

¹ University of Texas at Austin Dell Medical School, Austin, TX, USA.
² Austin Retina Associates, Austin, TX, USA.

Abstract

Purpose: We report a case of vitreoretinal lymphoma as the initial presentation of diffuse large B-cell lymphoma of the breast.

Methods: A case report is presented.

Results: A 72-year-old woman was referred for evaluation of vitritis in both eyes. Diagnostic vitrectomy and pathology workup demonstrated atypical lymphoid cells consistent with the presence of diffuse large B-cell lymphoma. Brain magnetic resonance imaging and lumbar puncture findings were negative for central nervous system lymphoma. Positron emission tomography/computed tomography imaging showed a mass in the left breast, and breast biopsy confirmed aggressive B-cell lymphoma.

Conclusions: When vitreoretinal lymphoma is diagnosed, it is important to evaluate for other forms of systemic lymphoma in addition to central nervous system lymphoma.

Keywords: DLBCL; breast; lymphoma; malignancy; uveitis; vitritis.

Publication types

Case Reports