Development of a Pt-graphene nanocomposite-based solid-phase extraction coupled with ultra-performance liquid chromatography-tandem mass spectrometry for the determination of carbamate pesticides in fish

Anal Sci. 2023 Jul;39(7):1129-1142. doi: 10.1007/s44211-023-00322-8. Epub 2023 Mar 31.

Abstract

In the present work, a potential solid-phase extraction (SPE) material based on graphene anchored with platinum nanoparticles (Pt-Graphene) was prepared and characterized by scanning electron micrographs and transmission electron micrograph. The carbamates residues in fish were enriched by SPE filled with Pt-Graphene and detected by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The proposed extraction protocol exhibited satisfactory recoveries (76.5-115.6%), low limit of quantitation values in μg kg-1 level, and good precision for the studied ten carbamates. These results demonstrated the feasibility of the proposed protocol. The developed Pt-Graphene nanoparticles showed excellent performance for extracting analytes at trace levels, indicating that it could be used as a potential SPE sorbent in food residue analysis.

Keywords: Carbamates; Fish; Pt-Graphene nanocomposite; Solid-phase extraction; UPLC–MS/MS.

MeSH terms

  • Animals
  • Carbamates / analysis
  • Carbamates / chemistry
  • Chromatography, High Pressure Liquid / methods
  • Chromatography, Liquid / methods
  • Graphite* / chemistry
  • Metal Nanoparticles* / analysis
  • Pesticides* / analysis
  • Platinum
  • Solid Phase Extraction / methods
  • Tandem Mass Spectrometry / methods

Substances

  • Graphite
  • Platinum
  • Pesticides
  • Carbamates