Bilateral medial medullary infarction with intravenous thrombolytic therapy: A case report

Medicine (Baltimore). 2023 Mar 31;102(13):e33375. doi: 10.1097/MD.0000000000033375.

Abstract

Rationale: Bilateral medial medullary infarction is a rare stroke subtype. To investigate its clinical manifestations, etiology, imaging features and thrombolytic effect, We here in reported a patient with acute ischemic stroke in the bilateral medial medullary and reviewed the related literatures.

Patients concern: A 64-year-old female was taken to our hospital after 4.5 hours of dizziness in the morning, followed by somnolence and limb weakness. She gradually worsened into a rapidly progressive tetraparesis and slurred speech.

Diagnoses: Diffusion weighted imaging exhibited a "heart appearance" sign in bilateral medial medulla oblongata, and high-resolution magnetic resonance imaging suggested the left vertebral artery-4 thromboembolism.

Interventions: Timely intravenous thrombolysis was performed.

Outcome: After intravenous thrombolysis, the patient's symptoms did not worsen in a short time. Although the symptoms were aggravated in the later stage, they were alleviated after active treatment.

Lessons: Diffusion weighted imaging can assist in the early diagnosis of bilateral medial medullary infarction, which will help in the decision to proceed with intravenous thrombolysis therapy. High-resolution magnetic resonance imaging should be improved as soon as possible, which can provide basis for the next intravascular interventional therapy.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Fibrinolytic Agents / therapeutic use
  • Humans
  • Infarction / complications
  • Ischemic Stroke* / complications
  • Magnetic Resonance Imaging / methods
  • Medulla Oblongata / diagnostic imaging
  • Medulla Oblongata / pathology
  • Middle Aged
  • Stroke* / etiology
  • Thrombolytic Therapy / adverse effects

Substances

  • Fibrinolytic Agents