In this study, the residual behavior and safety of cyantraniliprole and indoxacarb applied to wild garlic (Allium vineale) were investigated. Samples were harvested after treatments of 0, 3, 7, and 14 days, then were prepared and extracted following the QuEChERS method and analyzed by UPLC-MS/MS. The linearity (R2 ≥ 0.99) of the calibration curves was excellent for both compounds. The average recoveries of cyantraniliprole and indoxacarb at two spiking concentrations (0.01 and 0.1 mg/kg) ranged from 94.2% to 111.4%. The relative standard deviation value was below 10%. The initial concentrations of cyantraniliprole and indoxacarb in wild garlic were degraded to 75% and 93% after seven days. The average half-lives were 1.83 and 1.14 days for cyantraniliprole and indoxacarb, respectively. The preharvest intervals (PHIs) for the two pesticides in wild garlic are recommended as two treatments seven days before harvest. The safety assessment data indicated that the percent acceptable daily intakes of cyantraniliprole and indoxacarb were 0.3 × 10-4% and 6.7 × 10-2%, respectively, in wild garlic. The theoretical maximum daily intake value of cyantraniliprole was 9.80%, and that of indoxacarb was 60.54%. Both compounds' residues in wild garlic pose low health risks to consumers. The findings of the current investigation provide essential data for the safe use of cyantraniliprole and indoxacarb in wild garlic.
Keywords: MRLs; PHI; UPLC-MS/MS; insecticides; safety assessment.