Applications of Antioxidant Secondary Metabolites of Sargassum spp

Mar Drugs. 2023 Mar 9;21(3):172. doi: 10.3390/md21030172.

Abstract

Sargassum is one of the largest and most diverse genus of brown seaweeds, comprising of around 400 taxonomically accepted species. Many species of this genus have long been a part of human culture with applications as food, feed, and remedies in folk medicine. Apart from their high nutritional value, these seaweeds are also a well-known reservoir of natural antioxidant compounds of great interest, including polyphenols, carotenoids, meroterpenoids, phytosterols, and several others. Such compounds provide a valuable contribution to innovation that can translate, for instance, into the development of new ingredients for preventing product deterioration, particularly in food products, cosmetics or biostimulants to boost crops production and tolerance to abiotic stress. This manuscript revises the chemical composition of Sargassum seaweeds, highlighting their antioxidant secondary metabolites, their mechanism of action, and multiple applications in fields, including agriculture, food, and health.

Keywords: brown seaweeds; cosmetic; functional foods; phenolic compounds; phlorotannins; phytosterols; terpenoids.

Publication types

  • Review

MeSH terms

  • Antioxidants / chemistry
  • Antioxidants / pharmacology
  • Carotenoids
  • Humans
  • Polyphenols / pharmacology
  • Sargassum* / chemistry
  • Seaweed* / chemistry

Substances

  • Antioxidants
  • Polyphenols
  • Carotenoids

Grants and funding

This work received financial support from PT national funds (FCT/MCTES, Fundação para a Ciência e Tecnologia and Ministério da Ciência, Tecnologia e Ensino Superior) through the projects UIDB/50006/2020 and UIDP/50006/2020. S.S. thanks FCT for funding through program DL 57/2016–Norma transitória (Ref. SFRH/BPD/74299/2010). M.D.C. and S.M.C thank LAQV-REQUIMTE for research contract. R.S.-R thanks FCT/MCTES and ESF (European Social Fund) through NORTE 2020 (Programa Operacional Região Norte) for her PhD grant ref. 2022.14518.BD.