Recurrent reversible in-stent-stenosis after flow diverter treatment

Neuroradiology. 2023 Jul;65(7):1173-1177. doi: 10.1007/s00234-023-03144-7. Epub 2023 Mar 28.

Abstract

Flow diverter stents (FDS) are well established in the treatment of intracranial aneurysms which are difficult to treat with conventional endovascular techniques. However, they carry a relatively high risk of specific complications compared to conventional stents. A minor but frequent finding is the occurrence of reversible in-stent-stenosis (ISS) that tend to resolve spontaneously over time. Here, we report the case of a patient in their 30s who was treated with FDS for bilateral paraophthalmic internal carotid artery (ICA) aneurysms. ISS were found at the respective early follow-up examinations on both sides and had resolved at the 1-year follow-up examinations. Surprisingly ISS reoccurred at both sides in later follow-up examinations and again resolved spontaneously. The recurrence of ISS after resolution is a finding that has not been described previously. Its incidence and further development should be investigated systematically. This might contribute to our understanding of the mechanisms underlying the effect of FDS.

Keywords: Flow diverter stent; In-stent-stenosis; Intracranial aneurysm.

Publication types

  • Case Reports

MeSH terms

  • Carotid Artery Diseases* / therapy
  • Cerebral Angiography
  • Constriction, Pathologic / complications
  • Embolization, Therapeutic* / methods
  • Endovascular Procedures* / methods
  • Humans
  • Intracranial Aneurysm* / complications
  • Intracranial Aneurysm* / diagnostic imaging
  • Intracranial Aneurysm* / therapy
  • Retrospective Studies
  • Stents / adverse effects
  • Treatment Outcome