Synovial calprotectin: A potentially useful biomarker for the diagnosis of Kingella kingae native arthritis

Anne-Gallë Leroy; Pascale Bémer; Cyrille Decante; Louise Ruffier d'Epenoux; Eve Tessier; Vincent Crenn; Aurélie Guillouzouic; Stéphane Corvec; CRIOGO Microbiology Study Group

doi:10.1002/ccr3.7106

Synovial calprotectin: A potentially useful biomarker for the diagnosis of Kingella kingae native arthritis

Clin Case Rep. 2023 Mar 24;11(3):e7106. doi: 10.1002/ccr3.7106. eCollection 2023 Mar.

Authors

Anne-Gallë Leroy^{1

2

3}, Pascale Bémer^{1

3}, Cyrille Decante⁴, Louise Ruffier d'Epenoux^{1

3

5}, Eve Tessier¹, Vincent Crenn^{3

6}, Aurélie Guillouzouic¹, Stéphane Corvec^{1

3

5

7}; CRIOGO Microbiology Study Group

Collaborators

CRIOGO Microbiology Study Group:
Didier Tandé, Anne Gougeon, Vincent Cattoir, Chloé Plouzeau, Carole Lemarié, Racheal Chenouard, Marie-Frédérique Lartigue

Affiliations

¹ Service de Bactériologie et des Contrôles Microbiologiques CHU Nantes, Nantes Université Nantes France.
² Laboratoire EA 3826 « Thérapeutiques cliniques et expérimentales des infections », IRS2-Nantes Biotech Nantes Université Nantes France.
³ Nantes study group member of CRIOGO (Centre de Référence des Infections Ostéo-articulaires du Grand Ouest) Nantes France.
⁴ CHU Nantes, Service de Chirurgie Orthopédique Pédiatrique Nantes Université Nantes France.
⁵ Université de Nantes, CHU Nantes Nantes France.
⁶ CHU Nantes, CCOT, service d'orthopédie Nantes Université Nantes France.
⁷ ESGIAI (ESCMID Study Group for Implant-Associated Infections) member Nantes France.

Abstract

Kingella kingae is a bacteria involved in developing arthritis in children. Its diagnosis remains difficult. We report a case for which a new biomarker, calprotectin measured in the synovial fluid, was strongly positive and a specific molecular test was the only way to diagnose it specifically.

Keywords: Kingella kingae; calprotectin; septic native arthritis.

Publication types

Case Reports